Because Gold Kryptonite has appeared in the chronicles only infrequently, data concerning it is sparse beyond the fact that its radiations can be shielded by lead (S No. 157/1, Nov 1962: "The Super Revenge of the Phantom Zone Prisoner!"; S No. 179/2, Aug 1965: "The Menace of Gold Kryptonite!"). In August 1965, it is explained that a Kryptonian's loss of super-powers due to Gold-Kryptonite exposure would invariably be inherited by his or her offspring, thereby rendering the offspring incapable of acquiring super-powers in those environments—like that of Earth—where Kryptonian survivors normally acquire them (S No. 179/2, Aug 1965: "The Menace of Gold Kryptonite!"). However, in September 1986, in an imaginary story, it is shown that ten years after Superman has lost his powers due to exposure to a massive dose of Gold Kryptonite, his infant son is able to squeeze a lump of coal into a diamond (Act No. 583, Sep 1986: "Whatever Happened to the Man of Tomorrow?"--Pt. II).
Several Kryptonian survivors have lost their super-powers through exposure to Gold Kryptonite, including the Kryptonian scientist Quex-Ul, released from the Phantom Zone in November 1962 (S No. 157/1: "The Super-Revenge of the Phantom Zone Prisoner!") and a Kandorian couple named Jay-Ree and Joenne (See Kandor). Other than loss of their super-powers, the Kandorian couple appear to have experienced no ill effects from their Gold Kryptonite exposure (S No. 172, Aug 1965: "The Menace of Gold Kryptonite!"), but Quex-Ul's loss of super-powers was accompanied by "permanent amnesia" resulting from damage inflicted by the Gold Kryptonite to "some of his brain's memory cells" (S No. 157/1, Nov 1962: "The Super-Revenge of the Phantom Zone Prisoner").