In September 1985, Clark Kent is infected by this fungus which grows steadily worse until he loses control of his powers and senses his death is imminent. Not wanting to be pitied in his delirium, he flees to the American rural south where he finally collapses near a swamp.
However, while in the final stages of the infection, Swamp Thing finds Clark and manages to stop the infection and cure him (DCCP No. 85, Sep 1985: "The Jungle Line!").